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CYP27B1 antibody (AA 25-195)
CYP27B1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CYP27B1 Antibody
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Target
See all CYP27B1 Antibodies
CYP27B1
(Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
Binding Specificity
All epitopes for CYP27B1 antibodies
AA 25-195
Reactivity
All reactivities for CYP27B1 antibodies
Human
Host
All hosts for CYP27B1 antibodies
Rabbit
Clonality
All clonalities for CYP27B1 antibodies
Polyclonal
Conjugate
All conjugates for CYP27B1 antibodies
This CYP27B1 antibody is un-conjugated
Application
All applications for CYP27B1 antibodies
Western Blotting (WB)
Sequence
LGYREYHSAR RSLADIPGPS TPSFLAELFC KGGLSRLHEL QVQGAAHFGP VWLASFGTVR TVYVAAPALV EELLRQEGPR PERCSFSPWT EHRRCRQRAC GLLTAEGEEW QRLRSLLAPL LLRPQAAARY AGTLNNVVCD LVRRLRRQRG RGTGPPALVR DVAGEFYKFG L
Cross-Reactivity
Human, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-195 of human CYP27B1 (NP_000776.1).
Isotype
IgG
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Discover our top product CYP27B1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CYP27B1
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Target
CYP27B1
(Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
Alternative Name
CYP27B1 (CYP27B1 Products )
Synonyms
cp2b antibody, cyp1 antibody, cyp1alpha antibody, cyp27b antibody, p450c1 antibody, pddr antibody, vdd1 antibody, vddr antibody, vddri antibody, vdr antibody, CP2B antibody, CYP1 antibody, CYP1alpha antibody, CYP27B antibody, P450c1 antibody, PDDR antibody, VDD1 antibody, VDDR antibody, VDDRI antibody, VDR antibody, Cyp40 antibody, Cp2b antibody, Cyp1 antibody, Cyp27b antibody, Pddr antibody, Vdd1 antibody, Vddr antibody, VddrI antibody, Vdr antibody, cytochrome P450 family 27 subfamily B member 1 antibody, cytochrome P450, family 27, subfamily B, polypeptide 1 antibody, cytochrome P450, family 27, subfamily b, polypeptide 1 antibody, cyp27b1 antibody, CYP27B1 antibody, Cyp27b1 antibody
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.,CYP27B1,CP2B,CYP1,CYP1alpha,CYP27B,P450c1,PDDR,VDD1,VDDR,VDDRI,VDR,CYP27B1
Molecular Weight
56 kDa
Gene ID
1594
UniProt
O15528
Pathways
Metabolism of Steroid Hormones and Vitamin D
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