Thrombopoietin antibody (AA 22-349)
-
- Target See all Thrombopoietin (THPO) Antibodies
- Thrombopoietin (THPO)
-
Binding Specificity
- AA 22-349
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Thrombopoietin antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QGRTTAHKDP NAIFLSFQHL LRGKVRFLML VGGSTLCVRR APPTTAVPSR TSLVLTLNEL PNRTSGLLET NFTASARTTG SGLLKWQQGF RAKIPGLLNQ TSRSLDQIPG YLNRIHELLN GTRGLFPGPS RRTLGAPDIS SGTSDTGSLP PNLQPGYSPS PTHPPTGQYT LFPLPPTLPT PVVQLHPLLP DPSAPTPTPT SPLLNTSYTH SQNLSQEG
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 22-349 of human THPO (NP_001171068.1).
- Isotype
- IgG
- Top Product
- Discover our top product THPO Primary Antibody
-
-
- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- Thrombopoietin (THPO)
- Alternative Name
- THPO (THPO Products)
- Synonyms
- MGDF antibody, MKCSF antibody, ML antibody, MPLLG antibody, THCYT1 antibody, TPO antibody, Mgdf antibody, Ml antibody, Mpllg antibody, Tpo antibody, Tpo1 antibody, Tpo2 antibody, Tpo3 antibody, Tpo4 antibody, tpo antibody, LOC100231762 antibody, thrombopoietin antibody, THPO antibody, Thpo antibody, thpo antibody
- Background
- Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.,THPO,MGDF,MKCSF,ML,MPLLG,THCYT1,TPO,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Blood,THPO
- Molecular Weight
- 33 kDa/37 kDa
- Gene ID
- 7066
- UniProt
- P40225
- Pathways
- JAK-STAT Signaling, Hormone Activity
-