EPH Receptor A3 antibody (AA 400-545)

Catalog No. ABIN6224468

Product Details anti-EPH Receptor A3 Antibody

Target: EPH Receptor A3 (EPHA3)

Binding Specificity: AA 400-545

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LAHTNYTFEI DAVNGVSELS SPPRQFAAVS ITTNQAAPSP VLTIKKDRTS RNSISLSWQE PEHPNGIILD YEVKYYEKQE QETSYTILRA RGTNVTISSL KPDTIYVFQI RARTAAGYGT NSRKFEFETS PDSFSISGES SQVVMI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-545 of human EPHA3 (NP_005224.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Alternative Name: EPHA3 (EPHA3 Products)

Synonyms: EK4 antibody, ETK antibody, ETK1 antibody, HEK antibody, HEK4 antibody, TYRO4 antibody, EPHA3 antibody, AW492086 antibody, Cek4 antibody, End3 antibody, Hek antibody, Hek4 antibody, Mek4 antibody, Tyro4 antibody, CEK4 antibody, EPH receptor A3 antibody, ephrin type-A receptor 3 antibody, Eph receptor A3 antibody, EPHA3 antibody, LOC100439679 antibody, Epha3 antibody

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.,EK4,ETK,HEK,ETK1,HEK4,TYRO4,EPHA3,Signal Transduction,Kinase,Tyrosine kinases,Neuroscience,Cell Type Marker,Cardiovascular,Angiogenesis,Neuron marker,Growth Cone,EPHA3

Molecular Weight: 60 kDa/110 kDa

Gene ID: 2042

UniProt: P29320

Pathways: RTK Signaling, Regulation of Cell Size