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MME antibody (AA 472-505)

Name: MME antibody (AA 472-505)
SKU: ABIN6577253
Price: 181.5 USD
Availability: InStock

MME Reactivity: Human FACS, WB, IHC (p) Host: Mouse Monoclonal 965CT9-1-1 unconjugated

All lanes : Anti-E Antibody (Center) at 1:4000 dilution Lane 1: Human placenta lysate Lane 2: Ramos whole cell lysate Lane 3: Human kidney lysate Lysates/proteins at 20 μg per lane. (MME antibody (AA 472-505))

Immunohistochemical analysis of paraffin-embedded human kidney tissue using (ABIN6243087 and ABIN6577253) performed on the Leica® BOND RXm. (MME antibody (AA 472-505))

IHC (p)

Immunohistochemical analysis of paraffin-embedded Human kidney section using Pink1 (ABIN6243087 and ABIN6577253). (MME antibody (AA 472-505))

IHC

Overlay histogram showing Jurkat cells stained with (ABIN6243087 and ABIN6577253)(green line). (MME antibody (AA 472-505))

FACS

4 images

Catalog No. ABIN6577253

Datasheet as PDF

Target See all MME Antibodies

MME (Membrane Metallo-Endopeptidase (MME))
Binding Specificity
16

14

9

8

8

7

7

7

6

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 472-505
Reactivity
201

57

50

3

2

2

2

2

2

1

1

1

1
Human
Host
109

97

2
Mouse
Compatible Secondaries
Clonality
105

102

2
Monoclonal
Conjugate
104

19

17

13

9

6

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
Application
131

92

78

67

35

27

20

20

13

13

10

8

5

5

5

3

2

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This MME antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of human MME.

Clone

965CT9-1-1

Isotype

IgG1 kappa

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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:4000. IHC: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Target

MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name

MME (MME Products)

Synonyms

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

Target Type

Chemical

Background

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675, PubMed:< a href="http://www.uniprot.org/citations/8168535" target="_blank">8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:< a href="http://www.uniprot.org/citations/17101991" target="_blank">17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:< a href="http://www.uniprot.org/citations/2531377" target="_blank">2531377, PubMed:< a href="http://www.uniprot.org/citations/2972276" target="_blank">2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:< a href="http://www.uniprot.org/citations/20876573" target="_blank">20876573).

Molecular Weight

85514

UniProt

P08473

Pathways

RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration