This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-305 amino acids from the Central region of human TXNRD1.
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.