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Podoplanin antibody (AA 24-126)
PDPN
Reactivity: Human
WB, FACS, IF, IHC (p)
Host: Mouse
Monoclonal
PDPN-1433
unconjugated
Product Details anti-Podoplanin Antibody
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Target
See all Podoplanin (PDPN) Antibodies
Podoplanin (PDPN)
Binding Specificity
All epitopes for Podoplanin antibodies
AA 24-126
Reactivity
All reactivities for Podoplanin antibodies
Human
Host
All hosts for Podoplanin antibodies
Mouse
Clonality
All clonalities for Podoplanin antibodies
Monoclonal
Conjugate
All conjugates for Podoplanin antibodies
This Podoplanin antibody is un-conjugated
Application
All applications for Podoplanin antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Protein G affinity chromatography
Immunogen
A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.
Clone
PDPN-1433
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
WB: 0.5-1 μg/mL IF: 0.5-1 μg/mL Flow Cytometry: 0.5-1 μg/million cells in 0.1ml IHC (FFPE): 0.5-1 μg/mL for 30 min at RT Optimal dilution of the Podoplanin antibody should be determined by the researcher.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target Details for Podoplanin
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Target
Podoplanin (PDPN)
Alternative Name
Podoplanin (PDPN Products )
Synonyms
PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
Background
Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
Gene ID
10630
UniProt
Q86YL7
Pathways
Dicarboxylic Acid Transport
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