LGALS1/Galectin 1 antibody (AA 12-108)

Catalog No. ABIN6252495

Product Details anti-LGALS1/Galectin 1 Antibody

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Binding Specificity: AA 12-108

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGALS1/Galectin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Clone: GAL1-1831

Isotype: IgG1 lambda

Application Details

Application Notes: ELISA: 2-4 μg/mL, order the BSA-free formulation for coating

IF: 1-2 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

WB: 0.5-1 μg/mL

IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Titering of the Galectin 1 antibody may be required for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Alternative Name: Galectin 1 (LGALS1 Products)

Synonyms: GAL1 antibody, GBP antibody, Galectin-1 antibody, LGAS1 antibody, LGALS1 antibody, MGC64502 antibody, GB10026 antibody, AA410090 antibody, Gal-1 antibody, Galbp antibody, L-14.5 antibody, L14 antibody, Lect14 antibody, galectin-1 antibody, Galaptin antibody, galectin 1 antibody, galectin-1 antibody, lectin, galactoside-binding, soluble, 1 L homeolog antibody, protein enabled antibody, lectin, galactose binding, soluble 1 antibody, LGALS1 antibody, Lgals1 antibody, CC1G_05003 antibody, CC1G_05004 antibody, lgals1.L antibody, LOC408848 antibody

Background: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Gene ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis