Nkx2-2 antibody (AA 1-119)
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- Target See all Nkx2-2 Antibodies
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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Binding Specificity
- AA 1-119
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Nkx2-2 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogen
- A human partial recombinant protein corresponding to amino acids 1-119 was used as the immunogen for this NKX2.2 antibody.
- Clone
- NX2-1524
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product Nkx2-2 Primary Antibody
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- Application Notes
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Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT
Titering of the NKX2.2 antibody may be required for optimal performance. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Target
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
- Alternative Name
- NKX2.2 (Nkx2-2 Products)
- Synonyms
- XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
- Background
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
- Gene ID
- 4821
- UniProt
- O95096
- Pathways
- Dopaminergic Neurogenesis
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