IL1RL1 antibody (C-Term)

Catalog No. ABIN6252733

Product Details anti-IL1RL1 Antibody

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Affinity Chromatography

Immunogen: A recombinant protein fragment from the C-terminal region of human IL1RL1 was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 2-5 μg/mL

Provided assay concentrations are suggestions only, IL1RL1 antibody titration may be required for optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for IL1RL1

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Alternative Name: IL1RL1 (IL1RL1 Products)

Synonyms: DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, FIT-1 antibody, IL33R antibody, ST2 antibody, ST2V antibody, FIT1 antibody, interleukin 1 receptor-like 1 antibody, interleukin 1 receptor like 1 antibody, Il1rl1 antibody, IL1RL1 antibody

Background: IL1RL1 (Interleukin 1 receptor-like 1), also known as ST2 and ST2V, is a member of the IL1R family and TLR superfamily. TIR proteins initiate the innate immune response through NF-kB. Unlike other TIR proteins, IL1RL1 doesn't activate NF-kB. Instead, it promotes endotoxin tolerance through suppressive interaction with TLR4 and IL1R. This TLR inhibition also promotes a Th2 response.

Gene ID: 9173

UniProt: Q01638