×
For best experience we recommend to activate Javascript in your browser.
TCP1 alpha/CCTA antibody
TCP1
Reactivity: Human
IF, FACS, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TCP1 alpha/CCTA Antibody
(hide)
Target
See all TCP1 alpha/CCTA (TCP1) Antibodies
TCP1 alpha/CCTA (TCP1)
(T-Complex 1 (TCP1))
Reactivity
All reactivities for TCP1 alpha/CCTA antibodies
Human
Host
All hosts for TCP1 alpha/CCTA antibodies
Rabbit
Clonality
All clonalities for TCP1 alpha/CCTA antibodies
Polyclonal
Conjugate
All conjugates for TCP1 alpha/CCTA antibodies
This TCP1 alpha/CCTA antibody is un-conjugated
Application
All applications for TCP1 alpha/CCTA antibodies
Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Protein A affinity chromatography
Immunogen
Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
Isotype
IgG
Top Product
Discover our top product TCP1 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml Immunofluorescence: 1-2 μg/mL Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT The optimal dilution of the p63 antibody for each application should be determined by the researcher.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target Details for TCP1 alpha/CCTA
(hide)
Target
TCP1 alpha/CCTA (TCP1)
(T-Complex 1 (TCP1))
Alternative Name
p63 (TCP1 Products )
Synonyms
CCT-alpha antibody, CCT1 antibody, CCTa antibody, D6S230E antibody, TCP-1-alpha antibody, AI528772 antibody, CCT antibody, Cct1 antibody, Ccta antibody, TRic antibody, Tcp-1 antibody, Tp63 antibody, c-cpn antibody, p63 antibody, TRiC antibody, CCTalpha antibody, BEST:GH05123 antibody, CG5374 antibody, Dmel\\CG5374 antibody, T-cpl antibody, TCP-1alpha antibody, TCPA_DROME antibody, Tcp1 antibody, Tcp1-alpha antibody, gh05123 antibody, cct-alpha antibody, ccta antibody, tcp1 antibody, tcp1-a antibody, tcp1a antibody, tcp1alpha antibody, CHUNP6875 antibody, fa13h08 antibody, wu:fa13h08 antibody, wu:fc95g06 antibody, t-complex 1 antibody, T-complex protein 1 subunit alpha antibody, t-complex protein 1 antibody, Tcp1-like antibody, t-complex 1 S homeolog antibody, TCP1 antibody, cct-1 antibody, Tcp1 antibody, T-cp1 antibody, tcp1.S antibody, tcp1 antibody
Background
P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Gene ID
8626
UniProt
Q9H3D4
Recently viewed
(hide)