BAD antibody (pSer136)
Quick Overview for BAD antibody (pSer136) (ABIN6256132)
Target
See all BAD AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- pSer136
-
Specificity
- Phospho-BAD (Ser136) Antibody detects endogenous levels of BAD only when phosphorylated at Ser136 of mouse BAD or Ser99 of human BAD.
-
Predicted Reactivity
- Bovine,Horse,Sheep,Dog
-
Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
Immunogen
- A synthesized peptide derived from mouse BAD around the phosphorylation site of Ser136.
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Expiry Date
- 12 months
-
-
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
-
Alternative Name
- BAD
-
Background
-
Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Gene: BAD
-
Molecular Weight
- 23kDa
-
Gene ID
- 572
-
UniProt
- Q92934
-
Pathways
- MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
Target
-