FOXO3 antibody (pSer413)
Quick Overview for FOXO3 antibody (pSer413) (ABIN6256325)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer413
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Specificity
- Phospho-FoxO3a (Ser413) Antibody detects endogenous levels of FoxO3a.
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Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human FoxO3a around the phosphorylation site of Ser413.
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Isotype
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 Reactivity: Human WB, IF, ICC, IHC (p), IP Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 Reactivity: Human, Rat WB, IHC, IF, ICC, FACS Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Sheep, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivity: Human ELISA, IF, IHC (p) Host: Mouse Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Monoclonal 1E2 unconjugated Recombinant Antibody
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
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Expiry Date
- 12 months
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FoxO3a
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Background
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Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882). Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882). In response to metabolic stress, translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301).
Gene: FOXO3
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Molecular Weight
- 82-97kDa
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Gene ID
- 2309
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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