AKAP10 antibody (N-Term)
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- Target See all AKAP10 Antibodies
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AKAP10 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- AKAP10 Antibody detects endogenous levels of total AKAP10.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product AKAP10 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
- Alternative Name
- AKAP10 (AKAP10 Products)
- Synonyms
- MGC84612 antibody, AKAP10 antibody, fc10g11 antibody, wu:fc10g11 antibody, si:dkey-197m14.4 antibody, AKAP-10 antibody, D-AKAP-2 antibody, D-AKAP2 antibody, PRKA10 antibody, 1500031L16Rik antibody, B130049N18Rik antibody, D-akap2 antibody, Akap10 antibody, A-kinase anchoring protein 10 antibody, A-kinase anchoring protein 10 L homeolog antibody, A kinase (PRKA) anchor protein 10 antibody, AKAP10 antibody, akap10.L antibody, akap10 antibody, Akap10 antibody
- Background
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Description: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Gene: AKAP10
- Molecular Weight
- 73 kDa
- Gene ID
- 11216
- UniProt
- O43572
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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