APPL1 antibody (Internal Region)
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- Target See all APPL1 Antibodies
- APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APPL1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- APPL1 Antibody detects endogenous levels of total APPL1.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human APPL1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product APPL1 Primary Antibody
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- Application Notes
- WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
- Alternative Name
- APPL1 (APPL1 Products)
- Synonyms
- APPL antibody, DIP13alpha antibody, 2900057D21Rik antibody, 7330406P05Rik antibody, AI585782 antibody, AW209077 antibody, BB022931 antibody, C88264 antibody, DIP13 antibody, RGD1309388 antibody, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 antibody, adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 antibody, APPL1 antibody, Appl1 antibody
- Background
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Description: Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
Gene: APPL1
- Molecular Weight
- 80 kDa
- Gene ID
- 26060
- UniProt
- Q9UKG1
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