Progesterone Receptor antibody

Catalog No. ABIN625879

Product Details anti-Progesterone Receptor Antibody

Target: Progesterone Receptor (PGR)

Reactivity: Human, Rat, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)

Brand: IHC-plus™

Specificity: Equally recognizes two proteins: 116kD (triplet) and 81kD (singlet) which are identified as the hormone-binding high (B) and low (A) MW forms of human progesterone receptor. This antibody recognizes an epitope in the N-terminal half of human PgR. Species cross-reactivity: baboon, monkey, mouse and rat. Does not cross-react with guinea pig.

Purification: Protein G purified

Immunogen: Progesterone Receptor from a human endometrial carcinoma (EnCa 101) grown in athymic mice.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: IF, IHC, IHC-P (1:50), IP, WB (1 - 2 μg/mL)

Usage: Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation, and Sedimentation in sucrose gradients. Immunoprecipitation (NATIVE ONLY): 2 μg/mg protein lysate Using Protein G. Western Blot: 1-2 μg/mL for 2 hrs at RT. Positive control: T47D cells or breast carcinoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide. Sourced in Ascites.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR/Progesterone Receptor (PGR Products)

Synonyms: NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody

Background: Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: PGR, NR3C3, PR, Progesterone receptor

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration