STK10-A antibody (Internal Region)

Catalog No. ABIN6259091

Product Details anti-STK10-A Antibody

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK10-A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: STK10 Antibody detects endogenous levels of total STK10.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human STK10, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for STK10-A

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Alternative Name: STK10 (STK10-A Products)

Synonyms: LOK antibody, PRO2729 antibody, Gek1 antibody, Lok antibody, mKIAA4026 antibody, zgc:63495 antibody, plkk1 antibody, stk10 antibody, xPlkk1 antibody, serine/threonine kinase 10 antibody, serine/threonine kinase 10 S homeolog antibody, STK10 antibody, Stk10 antibody, stk10 antibody, stk10.S antibody

Background:

Description: Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro, however such data require additional evidences in vivo.

Gene: STK10

Molecular Weight: 120 kDa

Gene ID: 6793

UniProt: O94804