5HT1D antibody (Internal Region)

Catalog No. ABIN6259445

Product Details anti-5HT1D Antibody

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Binding Specificity: Internal Region

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1D antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: 5HT1D Receptor Antibody detects endogenous levels of total 5HT1D Receptor.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human 5HT1D Receptor, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for 5HT1D

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Alternative Name: HTR1D (HTR1D Products)

Synonyms: AI853647 antibody, Gpcr14 antibody, Htr1db antibody, 5-HT1D antibody, HT1DA antibody, HTR1DA antibody, HTRL antibody, RDC4 antibody, 5HT1D antibody, 5-HT-1D antibody, 5-hydroxytryptamine (serotonin) receptor 1D antibody, 5-hydroxytryptamine receptor 1D antibody, Htr1d antibody, HTR1D antibody

Background:

Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.

Gene: HTR1D

Molecular Weight: 45 kDa

Gene ID: 3352

UniProt: P28221

Pathways: JAK-STAT Signaling