MIB2 antibody (Internal Region)
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- Target See all MIB2 Antibodies
- MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MIB2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- MIB2 Antibody detects endogenous levels of total MIB2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MIB2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MIB2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))
- Alternative Name
- MIB2 (MIB2 Products)
- Synonyms
- ZZANK1 antibody, ZZZ5 antibody, 2210008I11Rik antibody, Zzank1 antibody, skd antibody, mib2 antibody, mindbomb E3 ubiquitin protein ligase 2 antibody, mindbomb E3 ubiquitin protein ligase 2 S homeolog antibody, MIB2 antibody, Mib2 antibody, mib2 antibody, mib2.S antibody
- Background
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
Gene: MIB2
- Molecular Weight
- ?110 kDa
- Gene ID
- 142678
- UniProt
- Q96AX9
- Pathways
- Notch Signaling
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