ARHGEF7 antibody (Internal Region)
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- Target See all ARHGEF7 Antibodies
- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARHGEF7 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- ARHGEF7 Antibody detects endogenous levels of total ARHGEF7.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ARHGEF7, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARHGEF7 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
- Alternative Name
- ARHGEF7 (ARHGEF7 Products)
- Synonyms
- BETA-PIX antibody, COOL-1 antibody, COOL1 antibody, Nbla10314 antibody, P50 antibody, P50BP antibody, P85 antibody, P85COOL1 antibody, P85SPR antibody, PAK3 antibody, PIXB antibody, cool1 antibody, p50 antibody, p85 antibody, pak3 antibody, pixb antibody, ARHGEF7 antibody, P85spr antibody, Pak3bp antibody, Cool antibody, PIX antibody, betaPix antibody, betaPix-b antibody, betaPix-c antibody, cool-1 antibody, mKIAA0142 antibody, p85Cool1 antibody, p85SPR antibody, arhgef7 antibody, bbh antibody, bpix antibody, im:7142367 antibody, wu:fc35h08 antibody, zgc:101775 antibody, Rho guanine nucleotide exchange factor 7 antibody, Rho guanine nucleotide exchange factor 7 S homeolog antibody, ankyrin repeat domain 10 antibody, Rho guanine nucleotide exchange factor (GEF7) antibody, Rho guanine nucleotide exchange factor (GEF) 7b antibody, ARHGEF7 antibody, arhgef7.S antibody, arhgef7 antibody, ANKRD10 antibody, Arhgef7 antibody, arhgef7b antibody
- Background
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Description: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Gene: ARHGEF7
- Molecular Weight
- 90kDa
- Gene ID
- 8874
- UniProt
- Q14155
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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