ASH2L antibody (Internal Region)

Catalog No. ABIN6260076

Product Details anti-ASH2L Antibody

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASH2L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: ASH2 Antibody detects endogenous levels of total ASH2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ASH2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Alternative Name: ASH2L (ASH2L Products)

Synonyms: ASH2 antibody, ASH2L1 antibody, ASH2L2 antibody, Bre2 antibody, fb34c06 antibody, fe38b04 antibody, fi20h02 antibody, wu:fb34c06 antibody, wu:fe38b04 antibody, wu:fi20h02 antibody, zgc:171444 antibody, ASH2L antibody, ash2-like antibody, ASH2 like histone lysine methyltransferase complex subunit antibody, ash2 (absent, small, or homeotic)-like (Drosophila) antibody, ash2 (absent, small, or homeotic)-like L homeolog antibody, ASH2L antibody, Ash2l antibody, ash2l antibody, ash2l.L antibody

Background:

Description: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Gene: ASH2L

Molecular Weight: 20 kDa.

Gene ID: 9070

UniProt: Q9UBL3