ARL6 antibody (Internal Region)
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- Target See all ARL6 Antibodies
- ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARL6 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- BBS3 Antibody detects endogenous levels of total BBS3.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human BBS3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARL6 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
- Alternative Name
- ARL6 (ARL6 Products)
- Synonyms
- BBS3 antibody, RP55 antibody, 1110018H24Rik antibody, 2210411E14Rik antibody, zgc:101762 antibody, arl6 antibody, ADP ribosylation factor like GTPase 6 antibody, ADP-ribosylation factor-like 6 antibody, ADP-ribosylation factor like GTPase 6 antibody, ADP-ribosylation factor-like protein 6 antibody, ADP ribosylation factor like GTPase 6 L homeolog antibody, ARL6 antibody, Arl6 antibody, arl6 antibody, arl-6 antibody, arl6.L antibody
- Background
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Description: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).
Gene: ARL6
- Molecular Weight
- 21 kDa
- Gene ID
- 84100
- UniProt
- Q9H0F7
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