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CARD8 antibody

CARD8 Reactivity: Human, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6276363
  • Target See all CARD8 Antibodies
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    Reactivity
    • 39
    • 11
    • 10
    Human, Mouse
    Host
    • 35
    • 4
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD8 antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    CARD8 Antibody detects endogenous levels of total CARD8
    Cross-Reactivity
    Human, Mouse (Murine)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CARD8
    Isotype
    IgG
    Top Product
    Discover our top product CARD8 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    Alternative Name
    CARD8 (CARD8 Products)
    Synonyms
    CARD8 antibody, CARDINAL antibody, DACAR antibody, DAKAR antibody, NDPP antibody, NDPP1 antibody, TUCAN antibody, caspase recruitment domain family, member 8 antibody, caspase recruitment domain-containing protein 8 antibody, caspase recruitment domain family member 8 antibody, CARD8 antibody, LOC718594 antibody
    Background

    Description: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

    Gene: CARD8

    Molecular Weight
    49kDa
    Gene ID
    22900
    UniProt
    Q9Y2G2
    Pathways
    Positive Regulation of Endopeptidase Activity
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