CDK11 antibody (Internal Region)

Catalog No. ABIN6260708

Product Details anti-CDK11 Antibody

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CDK11 Antibody detects endogenous levels of total CDK11.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDK11, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Alternative Name: CDK11A,CDK11B (CDK11B Products)

Synonyms: CDC2L1 antibody, CDK11 antibody, CDK11-p110 antibody, CDK11-p46 antibody, CDK11-p58 antibody, CLK-1 antibody, PK58 antibody, p58 antibody, p58CDC2L1 antibody, p58CLK-1 antibody, AA989746 antibody, Cdc11b antibody, Cdc2l1 antibody, Cdc2l2 antibody, Cdk11 antibody, CDC2L2 antibody, CDK11B antibody, cdc2l1 antibody, im:7142267 antibody, zgc:101589 antibody, cdc2l2 antibody, cdk11 antibody, cdk11-p110 antibody, cdk11-p46 antibody, cdk11-p58 antibody, cdk11b antibody, clk-1 antibody, p58cdc2l1 antibody, p58clk-1 antibody, pk58 antibody, cyclin dependent kinase 11B antibody, cyclin-dependent kinase 11B antibody, cyclin-dependent kinase 11B S homeolog antibody, CDK11B antibody, Cdk11b antibody, LOC489591 antibody, cdk11b antibody, cdk11b.S antibody

Background:

Description: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

Gene: CDK11A

Molecular Weight: 90kDa

Gene ID: 728642, 984

UniProt: Q9UQ88, P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase