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CHST14 antibody (Internal Region)

CHST14 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260831
  • Target See all CHST14 Antibodies
    CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
    Binding Specificity
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    Internal Region
    Reactivity
    • 24
    • 21
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHST14 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    CHST14 Antibody detects endogenous levels of total CHST14.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CHST14, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CHST14 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
    Alternative Name
    CHST14 (CHST14 Products)
    Synonyms
    ATCS antibody, D4ST1 antibody, HNK1ST antibody, 2600016L03Rik antibody, D4ST-1 antibody, D4st1 antibody, d4st1 antibody, MGC136487 antibody, wu:fc04a01 antibody, zgc:136487 antibody, carbohydrate sulfotransferase 14 antibody, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 antibody, CHST14 antibody, Chst14 antibody, chst14 antibody
    Background

    Description: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development.

    Gene: CHST14

    Molecular Weight
    43 kDa
    Gene ID
    113189
    UniProt
    Q8NCH0
    Pathways
    Glycosaminoglycan Metabolic Process
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