PTGS1 antibody (C-Term)

Catalog No. ABIN6260980

Product Details anti-PTGS1 Antibody

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Binding Specificity: C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Cox1 Antibody detects endogenous levels of total Cox1.

Predicted Reactivity: Pig,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cox1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PTGS1

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Alternative Name: PTGS1 (PTGS1 Products)

Synonyms: COX-1 antibody, cox-1 antibody, PTGS1 antibody, Ptgs1 antibody, COX1 antibody, Cox-1 antibody, Cox-3 antibody, PGHS-1 antibody, PHS 1 antibody, Pghs1 antibody, Cox1 antibody, Cox3 antibody, cox1 antibody, zCOX-1 antibody, COX3 antibody, PCOX1 antibody, PES-1 antibody, PGG/HS antibody, PGHS1 antibody, PHS1 antibody, PTGHS antibody, COX-3 antibody, prostaglandin-endoperoxide synthase 1 antibody, cyclooxygenase-1 antibody, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody, prostaglandin-endoperoxide synthase 1 S homeolog antibody, PTGS1 antibody, cox-1 antibody, Ptgs1 antibody, ptgs1 antibody, ptgs1.S antibody

Background:

Description: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Gene: PTGS1

Molecular Weight: 70kDa

Gene ID: 5742

UniProt: P23219