DP2 antibody (Internal Region)

Catalog No. ABIN6261359

Product Details anti-DP2 Antibody

Target: DP2 (TFDP2) (Transcription Factor Dp-2 (E2F Dimerization Partner 2) (TFDP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: DP-2 Antibody detects endogenous levels of total DP-2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DP-2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DP2

Target: DP2 (TFDP2) (Transcription Factor Dp-2 (E2F Dimerization Partner 2) (TFDP2))

Alternative Name: TFDP2 (TFDP2 Products)

Synonyms: dp2 antibody, dp-2 antibody, 1110029I05Rik antibody, A330080J22Rik antibody, DP-3 antibody, DP3 antibody, DP2 antibody, Tcfdp2 antibody, transcription factor Dp-2 antibody, transcription factor Dp-2 S homeolog antibody, transcription factor Dp 2 antibody, TFDP2 antibody, tfdp2 antibody, tfdp2.S antibody, Tfdp2 antibody

Background:

Description: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).

Gene: TFDP2

Molecular Weight: 49 kDa

Gene ID: 7029

UniProt: Q14188

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases