RNASE3 antibody

Catalog No. ABIN6261424

Product Details anti-RNASE3 Antibody

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASE3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: ECP Antibody detects endogenous levels of total ECP

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ECP

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for RNASE3

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Alternative Name: ECP (ECP Products)

Synonyms: ECP antibody, RNS3 antibody, ribonuclease A family member 3 antibody, RNASE3 antibody

Background:

Description: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Gene: RNASE3

Molecular Weight: 18 kDa

Gene ID: 6037

UniProt: P12724