HMOX1 antibody (Internal Region)

Catalog No. ABIN6262336

Product Details anti-HMOX1 Antibody

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: HO-1 Antibody detects endogenous levels of total HO-1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HO-1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-HMOX1 antibody (ABIN6262336)

Qiu, Ma, Wu, Ding: "DL-3-n-butylphthalide improves ventricular function, and prevents ventricular remodeling and arrhythmias in post-MI rats." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 391, Issue 6, pp. 627-637, (2018) (PubMed).

Waltz, Kautza, Luciano, Dyer, Stolz, Loughran, Neal, Sperry, Rosengart, Zuckerbraun: "Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2021645, (2018) (PubMed).

Target Details for HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Alternative Name: HMOX1 (HMOX1 Products)

Synonyms: HMOX1 antibody, ARABIDOPSIS THALIANA HEME OXYGENASE 1 antibody, ATHO1 antibody, F18A8.4 antibody, F18A8_4 antibody, GENOMES UNCOUPLED 2 antibody, GUN2 antibody, HEME OXYGENASE antibody, HEME OXYGENASE 1 antibody, HEME OXYGENASE 6 antibody, HO1 antibody, HY1 antibody, HY6 antibody, PLASTID HEME OXYGENASE antibody, REVERSAL OF THE DET PHENOTYPE 4 antibody, HO-1 antibody, wu:fc27c04 antibody, zgc:65984 antibody, D8Wsu38e antibody, Hemox antibody, Hmox antibody, Hsp32 antibody, HEOXG antibody, Heox antibody, Ho-1 antibody, Ho1 antibody, hsp32 antibody, MGC132176 antibody, Hmox1 antibody, HMOX1D antibody, HSP32 antibody, bK286B10 antibody, heme oxygenase 1 antibody, Plant heme oxygenase (decyclizing) family protein antibody, Heme oxygenase antibody, heme oxygenase antibody, heme oxygenase 1, chloroplastic antibody, heme oxygenase 1a antibody, heme oxygenase 1 L homeolog antibody, HMOX1 antibody, TED4 antibody, ho1 antibody, P9301_RS17555 antibody, A9601_RS17590 antibody, MAE_RS06565 antibody, HO1 antibody, hmox1a antibody, CPE0214 antibody, Cyan7425_2962 antibody, Hmox1 antibody, hmox1.L antibody, AM1_C0205 antibody, CC1G_11686 antibody, CpipJ_CPIJ007246 antibody

Background:

Description: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.

Gene: HMOX1

Molecular Weight: 33 kDa

Gene ID: 3162

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome