IGHG1 antibody
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- Target See all IGHG1 Antibodies
- IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IGHG1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- IGHG1 Antibody detects endogenous levels of total IGHG1
- Cross-Reactivity
- Human
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IGHG1
- Isotype
- IgG
- Top Product
- Discover our top product IGHG1 Primary Antibody
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- Application Notes
- WB 1:1000-3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
- Alternative Name
- IGHG1 (IGHG1 Products)
- Synonyms
- RGD1359539 antibody, IgG1 antibody, Igh-4 antibody, VH7183 antibody, immunoglobulin heavy constant gamma 1 antibody, immunoglobulin heavy constant gamma 1 (G1m marker) antibody, Ighg1 antibody, IGHG1 antibody
- Background
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Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Gene: IGHG1
- UniProt
- P01857
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