IL1RN antibody (Internal Region)
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- Target See all IL1RN Antibodies
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL1RN antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- IL1RN Antibody detects endogenous levels of total IL1RN.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IL1RN, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product IL1RN Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Alternative Name
- IL1RN (IL1RN Products)
- Synonyms
- DIRA antibody, ICIL-1RA antibody, IL-1RN antibody, IL-1ra antibody, IL-1ra3 antibody, IL1F3 antibody, IL1RA antibody, IRAP antibody, MVCD4 antibody, IRAP1 antibody, IL1RN antibody, IL-1RA antibody, F630041P17Rik antibody, interleukin 1 receptor antagonist antibody, interleukin 1 receptor antagonist-like antibody, IL1RN antibody, Il1rn antibody, IL1RNL antibody
- Background
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Description: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.
Gene: IL1RN
- Molecular Weight
- 20kDa
- Gene ID
- 3557
- UniProt
- P18510
- Pathways
- NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
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