LONP2 antibody (Internal Region)

Catalog No. ABIN6262996

Product Details anti-LONP2 Antibody

Target: LONP2 (Lon Peptidase 2, Peroxisomal (LONP2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LONP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: LONP2 Antibody detects endogenous levels of total LONP2.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human LONP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for LONP2

Target: LONP2 (Lon Peptidase 2, Peroxisomal (LONP2))

Alternative Name: LONP2 (LONP2 Products)

Synonyms: 1300002A08Rik antibody, AU015403 antibody, Lonp antibody, LRRGT00016 antibody, RGD1305466 antibody, LONP antibody, LONPL antibody, wu:fc51e03 antibody, zgc:92557 antibody, lon peptidase 2, peroxisomal antibody, lon peptidase 2, peroxisomal L homeolog antibody, LONP2 antibody, Lonp2 antibody, lonp2.L antibody, lonp2 antibody

Background:

Description: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.

Gene: LONP2

Molecular Weight: 95kDa

Gene ID: 83752

UniProt: Q86WA8