NFATC2IP antibody (Internal Region)
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- Target See all NFATC2IP Antibodies
- NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))
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Binding Specificity
- Internal Region
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFATC2IP antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- NFATc2IP Antibody detects endogenous levels of total NFATc2IP.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NFATc2IP, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NFATC2IP Primary Antibody
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- Application Notes
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))
- Alternative Name
- NFATC2IP (NFATC2IP Products)
- Synonyms
- wu:fj84d09 antibody, NFATC2IP antibody, D7Ertd304e antibody, NIP45 antibody, ESC2 antibody, RAD60 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein antibody, nuclear factor of activated T-cells 2 interacting protein antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein antibody, nfatc2ip antibody, NFATC2IP antibody, Nfatc2ip antibody
- Background
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Description: In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter, this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity).
Gene: NFATC2IP
- Molecular Weight
- 48kDa
- Gene ID
- 84901
- UniProt
- Q8NCF5
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