PNKP antibody (Internal Region)
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- Target See all PNKP Antibodies
- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PNKP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- PNKP Antibody detects endogenous levels of total PNKP.
- Predicted Reactivity
- Pig,Bovine
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PNKP, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PNKP Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
- Alternative Name
- PNKP (PNKP Products)
- Synonyms
- EIEE10 antibody, MCSZ antibody, PNK antibody, Tb06.28P18.320 antibody, 21.m03011 antibody, 1810009G08Rik antibody, polynucleotide kinase 3'-phosphatase antibody, hypothetical protein antibody, polynucleotide kinase 3'- phosphatase antibody, PNKP antibody, Pnkp antibody, Tc00.1047053507017.50 antibody, Tc00.1047053505807.190 antibody, Tb927.6.1580 antibody, BBOV_IV000690 antibody, CC1G_05202 antibody, PGTG_20262 antibody, PGTG_18987 antibody, pnkp.S antibody, pnkp antibody
- Background
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Description: Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
Gene: PNKP
- Molecular Weight
- 60kDa
- Gene ID
- 11284
- UniProt
- Q96T60
- Pathways
- DNA Damage Repair, Nucleotide Phosphorylation
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