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PSMB1 antibody (Internal Region)

PSMB1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264474
  • Target See all PSMB1 Antibodies
    PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 34
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 33
    • 1
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMB1 antibody is un-conjugated
    Application
    • 24
    • 19
    • 18
    • 10
    • 6
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    PSMB1 Antibody detects endogenous levels of total PSMB1.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PSMB1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PSMB1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
    Alternative Name
    PSMB1 (PSMB1 Products)
    Synonyms
    DDBDRAFT_0217063 antibody, DDBDRAFT_0232957 antibody, DDB_0217063 antibody, DDB_0232957 antibody, AA409053 antibody, C81484 antibody, Lmpc5 antibody, HC5 antibody, PMSB1 antibody, PSC5 antibody, wu:fc51f06 antibody, zgc:103665 antibody, proteasome subunit beta 1 antibody, 20S proteasome subunit beta-1 antibody, proteasome subunit beta type 1 antibody, proteasome (prosome, macropain) subunit, beta type 1 antibody, proteasome subunit beta 1 S homeolog antibody, psmb1 antibody, PSMB1 antibody, psmB1 antibody, LOC100286342 antibody, Psmb1 antibody, psmb1.S antibody
    Background

    Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

    Gene: PSMB1

    Molecular Weight
    26kDa
    Gene ID
    5689
    UniProt
    P20618
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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