PSMB2 antibody (Internal Region)
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- Target See all PSMB2 Antibodies
- PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMB2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- PSMB2 Antibody detects endogenous levels of total PSMB2.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PSMB2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PSMB2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))
- Alternative Name
- PSMB2 (PSMB2 Products)
- Synonyms
- HC7-I antibody, 19.m02268 antibody, DDBDRAFT_0190287 antibody, DDBDRAFT_0232958 antibody, DDB_0190287 antibody, DDB_0232958 antibody, Psmb2 antibody, ACYPI004276 antibody, AU045357 antibody, AW108089 antibody, C7-I antibody, D4Wsu33e antibody, zgc:92282 antibody, proteasome subunit beta 2 antibody, proteasome subunit beta type 2 antibody, proteasome beta 2 subunit antibody, putative proteasome beta 2 subunit antibody, 20S proteasome subunit beta-2 antibody, proteasome (prosome, macropain) subunit, beta type 2 antibody, proteasome subunit beta 2 L homeolog antibody, PSMB2 antibody, CNC04990 antibody, Tc00.1047053510287.30 antibody, Tc00.1047053503891.100 antibody, Tc00.1047053508461.430 antibody, LBRM_34_3820 antibody, LBRM_35_0400 antibody, BBOV_I004450 antibody, LMJF_36_0320 antibody, psmB2 antibody, Psmb2 antibody, psmb2 antibody, psmb2.L antibody
- Background
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Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Gene: PSMB2
- Molecular Weight
- 22kDa
- Gene ID
- 5690
- UniProt
- P49721
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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