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14-3-3 sigma/SFN antibody (Internal Region)

SFN Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265025
  • Target See all 14-3-3 sigma/SFN (SFN) Antibodies
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Binding Specificity
    • 15
    • 13
    • 11
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 103
    • 35
    • 28
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 93
    • 9
    • 2
    • 1
    Rabbit
    Clonality
    • 88
    • 17
    Polyclonal
    Conjugate
    • 48
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This 14-3-3 sigma/SFN antibody is un-conjugated
    Application
    • 86
    • 44
    • 38
    • 23
    • 17
    • 15
    • 14
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    14-3-3 sigma Antibody detects endogenous levels of total 14-3-3 sigma.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human 14-3-3 sigma, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SFN Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    Alternative Name
    SFN (SFN Products)
    Synonyms
    YWHAS antibody, Er antibody, Mme1 antibody, Ywhas antibody, stratifin antibody, SFN antibody, Sfn antibody
    Background

    Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

    Gene: SFN

    Molecular Weight
    28kDa
    Gene ID
    2810
    UniProt
    P31947
    Pathways
    p53 Signaling, Myometrial Relaxation and Contraction
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