SLC22A17 antibody (C-Term)

Catalog No. ABIN6265112

Product Details anti-SLC22A17 Antibody

Target: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A17 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: SLC22A17 Antibody detects endogenous levels of total SLC22A17.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC22A17, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC22A17

Target: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Alternative Name: SLC22A17 (SLC22A17 Products)

Synonyms: 1700094C23Rik antibody, 24p3R antibody, AU041908 antibody, AW555662 antibody, BOIT antibody, Boct antibody, mBOCT antibody, BOCT antibody, NGALR antibody, NGALR2 antibody, NGALR3 antibody, hBOIT antibody, rBOCT antibody, solute carrier family 22 member 17 antibody, solute carrier family 22 (organic cation transporter), member 17 antibody, solute carrier family 22, member 17 antibody, SLC22A17 antibody, Slc22a17 antibody

Background:

Description: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).

Gene: SLC22A17

Molecular Weight: 58 kDa

Gene ID: 51310

UniProt: Q8WUG5

Pathways: Transition Metal Ion Homeostasis