SNRPD3 antibody (Internal Region)

Catalog No. ABIN6265188

Product Details anti-SNRPD3 Antibody

Target: SNRPD3 (Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa (SNRPD3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: SmD3 Antibody detects endogenous levels of total SmD3.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SmD3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SNRPD3

Target: SNRPD3 (Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa (SNRPD3))

Alternative Name: SNRPD3 (SNRPD3 Products)

Synonyms: SMD3 antibody, Sm-D3 antibody, 1700043E15Rik antibody, 2310009E13Rik antibody, AW046420 antibody, CG8427 antibody, Dmel\\CG8427 antibody, SYM10 antibody, Sm D3 antibody, dD3 antibody, guf antibody, guf2 antibody, l(2)131/7 antibody, l(2)154/1 antibody, l(2)90/37 antibody, smD3 antibody, smd3 antibody, snRNP Sm D3 antibody, zgc:86943 antibody, small nuclear ribonucleoprotein D3 polypeptide antibody, small nuclear ribonucleoprotein D3 antibody, small nuclear ribonucleoprotein D3 polypeptide L homeolog antibody, Small ribonucleoprotein particle protein SmD3 antibody, SNRPD3 antibody, Snrpd3 antibody, snrpd3.L antibody, SmD3 antibody, snrpd3 antibody

Background:

Description: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.

Gene: SNRPD3

Molecular Weight: 14 kDa

Gene ID: 6634

UniProt: P62318

Pathways: Ribonucleoprotein Complex Subunit Organization