MAP4K6 antibody (Internal Region)
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- Target See all MAP4K6 (MINK1) Antibodies
- MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP4K6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- MINK1 Antibody detects endogenous levels of total MINK1.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MINK1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MINK1 Primary Antibody
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- Application Notes
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
- Alternative Name
- MINK1 (MINK1 Products)
- Synonyms
- MINK1 antibody, MINK antibody, B55 antibody, MAP4K6 antibody, YSK2 antibody, ZC3 antibody, hMINK antibody, hMINKbeta antibody, MEKKK 6 antibody, Map4k6 antibody, RP23-122P1.6 antibody, Ysk2 antibody, misshapen like kinase 1 antibody, misshapen-like kinase 1 antibody, misshapen-like kinase 1 (zebrafish) antibody, MINK1 antibody, Mink1 antibody
- Background
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Description: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.
Gene: MINK1
- Molecular Weight
- 150kDa
- Gene ID
- 50488
- UniProt
- Q8N4C8
- Pathways
- Synaptic Membrane
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