SYN1 antibody (Ser9)

Catalog No. ABIN6280125

Product Details anti-SYN1 Antibody

Target: SYN1 (Synapsin I (SYN1))

Binding Specificity: AA 1-80, Ser9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Synapsin I is a protein encoded by the SYN1 gene which is approximately 74,1 kDa. Synapsin I is localised to the Golgi apparatus and cell junction. It is involved in the neurotransmitter release cycle, MAPK-Erk pathway and the brain-derived neurotrophic factor signalling pathway. It is a neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton and is believed to function in the regulation of neurotransmitter release. It forms a complex with NOS1 and CAPON proteins and is necessary for specific nitric-oxide functions at a presynaptic level. Synapsin I is expressed in the nervous system, adrenal gland and eye. Mutations in the SYN1 gene may result in X-linked epilepsy. STJ95848 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of synapsin I protein.

Specificity: Synapsin I Polyclonal Antibody detects endogenous levels of Synapsin I protein.

Characteristics: Rabbit polyclonal to Synapsin I.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Synapsin I around the non-phosphorylation site of S9.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for SYN1

Target: SYN1 (Synapsin I (SYN1))

Alternative Name: Synapsin I (SYN1 Products)

Synonyms: SYN1a antibody, SYN1b antibody, SYNI antibody, Syn-1 antibody, SYN I antibody, si:dkey-90n12.3 antibody, synapsin I antibody, synapsin I L homeolog antibody, SYN1 antibody, Syn1 antibody, syn1.L antibody, syn1 antibody

Molecular Weight: 77 kDa

Gene ID: 6853

UniProt: P17600