ZIC1/2/3 antibody (Internal Region)

Catalog No. ABIN6282862

Product Details anti-ZIC1/2/3 Antibody

Target: ZIC1/2/3 (Zic1/2/3/4/5) (Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5))

Binding Specificity: AA 290-370, Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC1/2/3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to Zic1/2/3.

Specificity: Zic1/2/3 Polyclonal Antibody detects endogenous levels of Zic1/2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Zic1/2/3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000

Comment:

CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for ZIC1/2/3

Target: ZIC1/2/3 (Zic1/2/3/4/5) (Zic Family Member 1/2/3/4/5 (Zic1/2/3/4/5))

Alternative Name: Zic1/2/3 (Zic1/2/3/4/5 Products)

Molecular Weight: 51 kDa

Gene ID: 7545

UniProt: Q15915