FAP antibody (Internal Region)

Catalog No. ABIN6283232

Product Details anti-FAP Antibody

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Binding Specificity: AA 300-380, Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to Seprase.

Specificity: Seprase Polyclonal Antibody detects endogenous levels of Seprase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Seprase

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000

Comment:

Expressed in adipose tissue. Expressed in the dermal fibroblasts in the fetal skin. Expressed in the granulation tissue of healing wounds and on reactive stromal fibroblast in epithelial cancers. Expressed in activated fibroblast-like synoviocytes from inflamed synovial tissues. Expressed in activated hepatic stellate cells (HSC) and myofibroblasts from cirrhotic liver, but not detected in normal liver. Expressed in glioma cells (at protein level). Expressed in glioblastomas and glioma cells. Isoform 1 and isoform 2 are expressed in melanoma, carcinoma and fibroblast cell lines.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: Seprase (FAP Products)

Synonyms: fap-A antibody, gene 13 antibody, FAP antibody, fapa antibody, dppiv antibody, seprase antibody, DPPIV antibody, FAPA antibody, fibroblast activation protein antibody, fibroblast activation protein alpha L homeolog antibody, fibroblast activation protein alpha antibody, fibroblast activation protein, alpha antibody, prolyl endopeptidase FAP antibody, Fap antibody, fap.L antibody, FAP antibody, fap antibody, LOC100547273 antibody

Molecular Weight: 90/170 kDa

Gene ID: 2191

UniProt: Q12884

Pathways: Tube Formation