EEA1 antibody (N-Term)

Catalog No. ABIN6287381

Product Details anti-EEA1 Antibody

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: EEA1 is a protein encoded by the EEA1 gene which is approximately 162,5 kDa. EEA1 is localised to the cytoplasm and is involved in the innate immune system, activated TLR4 signalling and sorting endosome formation in CF. It binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. EEA1 is expressed in the liver, eye, heart, pancreas and adrenal gland. Mutations in the EEA1 gene may result in Bartonellosis and Cutaneous Lupus Erythematosus. STJ96393 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of EEA1 protein.

Specificity: EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein.

Characteristics: Rabbit polyclonal to EEA1.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human EEA1.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for EEA1

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Alternative Name: EEA1 (EEA1 Products)

Synonyms: MST105 antibody, MSTP105 antibody, ZFYVE2 antibody, im:7151048 antibody, si:ch211-276p10.2 antibody, A430109M19Rik antibody, B230358H09Rik antibody, early endosome antigen 1 antibody, early endosome antigen 1 S homeolog antibody, EEA1 antibody, eea1 antibody, Eea1 antibody, eea1.S antibody

Molecular Weight: 162 kDa

Gene ID: 8411

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades