CD2 antibody (N-Term)

Catalog No. ABIN6287430

Product Details anti-CD2 Antibody

Target: CD2

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: CD2 is a protein encoded by the CD2 gene which is approximately 39,4 kDa. CD2 is localised to the cell membrane. It is involved in PEDF induced signalling, the TGF-beta pathway, Akt signalling and ERK signalling. It is a surface antigen found on all peripheral blood T-cells. It interacts with LFA3 on antigen presenting cells to optimize immune recognition. CD2 is implicated in the triggering of T-cells with the cytoplasmic domain is implicated in the signalling function. CD2 is expressed in the spleen, pancreas, blood, kidney and lymph nodes. Mutations in the CD2 gene may result in immune defects. STJ96971 was developed from clone 3F3 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous CD2 proteins.

Specificity: The antibody detects endogenous CD2 proteins.

Characteristics: Mouse monoclonal to CD2.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Clone: 3F3

Isotype: IgG1

Application Details

Application Notes: IHC 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for CD2

Target: CD2

Alternative Name: CD2 (CD2 Products)

Synonyms: CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody

Gene ID: 914

UniProt: P06729