GLUT4 antibody (N-Term)

Catalog No. ABIN6287607

Product Details anti-GLUT4 Antibody

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Binding Specificity: AA 21-70, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUT4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Glut4 is a protein encoded by the SLC2A4 gene which is approximately 54,7 kDa. Glut4 is localised to the cell membrane and cytoplasm. It is involved in the transport of glucose, other sugars, bile salts, organic acids and metal ions and AMP-activated protein kinase signalling. This protein falls under the solute carrier family 2 and functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, it is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Glut4 is expressed in the skeletal and cardiac muscles, brown and white fat. Mutations in the SLC2A4 gene may be involved in diabetes mellitus. STJ96888 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Glut4 protein.

Specificity: Glut4 Polyclonal Antibody detects endogenous levels of Glut4 protein.

Characteristics: Rabbit polyclonal to Glut4.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Glut4.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:20000

Comment:

Skeletal and cardiac muscles, brown and white fat.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Alternative Name: Glut4 (SLC2A4 Products)

Synonyms: GLUT4 antibody, Glut-4 antibody, Glut4 antibody, glut4 antibody, slc2a4 antibody, SLC2A4 antibody, solute carrier family 2 member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antibody, SLC2A4 antibody, Slc2a4 antibody, GLUT4 antibody, slc2a4.L antibody

Gene ID: 6517

UniProt: P14672

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect