ANAPC2 antibody

Catalog No. ABIN6290063

Product Details anti-ANAPC2 Antibody

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human ANAPC2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ANAPC2

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Alternative Name: ANAPC2 (ANAPC2 Products)

Synonyms: anapc2 antibody, ANAPC2 antibody, DDBDRAFT_0203816 antibody, DDBDRAFT_0234264 antibody, DDB_0203816 antibody, DDB_0234264 antibody, si:ch73-203i15.5 antibody, APC2 antibody, RP11-350O14.5 antibody, 9230107K09Rik antibody, AL024279 antibody, Apc2 antibody, Emi4 antibody, Imi4 antibody, mKIAA1406 antibody, F28I8.30 antibody, F28I8_30 antibody, anaphase-promoting complex/cyclosome 2 antibody, anaphase promoting complex subunit 2 antibody, anaphase promoting complex subunit 2 L homeolog antibody, anaphase-promoting complex/cyclosome 2 antibody, Anaphase-promoting complex subunit 2 antibody, ANAPC2 antibody, anapc2.L antibody, anapc2 antibody, Anapc2 antibody, APC2 antibody, apc-2 antibody

Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Molecular Weight: 93.828 kDa

Gene ID: 29882

UniProt: Q9UJX6

Pathways: Regulation of Cell Size