Claudin 17 antibody

Catalog No. ABIN6290242

Product Details anti-Claudin 17 Antibody

Target: Claudin 17 (CLDN17)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 17 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human CLDN17

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

In the kidney, expressed in the proximal tubule and in the Henle's loop, In the distal convoluted tubule, not expressed in all tubules, Not detected in the collecting duct (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for Claudin 17

Target: Claudin 17 (CLDN17)

Alternative Name: CLDN17 (CLDN17 Products)

Synonyms: CLDN17 antibody, Claudin-17 antibody, zgc:173444 antibody, claudin 17 antibody, CLDN17 antibody, cldn17 antibody, Cldn17 antibody

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11.

Molecular Weight: 24.603 kDa

Gene ID: 26285

UniProt: P56750

Pathways: Cell-Cell Junction Organization, Hepatitis C