DKC1 antibody
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- Target See all DKC1 Antibodies
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DKC1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human DKC1
- Isotype
- IgG
- Top Product
- Discover our top product DKC1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Ubiquitously expressed
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
- Alternative Name
- DKC1 (DKC1 Products)
- Synonyms
- CBF5 antibody, DKC antibody, DKCX antibody, NAP57 antibody, NOLA4 antibody, XAP101 antibody, dyskerin antibody, fv62a07 antibody, wu:fa28f10 antibody, wu:fc87a02 antibody, wu:fi24a05 antibody, wu:fv62a07 antibody, zgc:110395 antibody, DKC1 antibody, cbf5 antibody, dkc antibody, nap57 antibody, nola4 antibody, xap101 antibody, BC068171 antibody, Nap57 antibody, AtCBF5 antibody, AtNAP57 antibody, homologue of NAP57 antibody, dyskerin pseudouridine synthase 1 antibody, microRNA 664b antibody, dyskeratosis congenita 1, dyskerin antibody, dyskeratosis congenita 1, dyskerin L homeolog antibody, homologue of NAP57 antibody, DKC1 antibody, MIR664B antibody, dkc1 antibody, dkc1.L antibody, Dkc1 antibody, NAP57 antibody
- Background
- This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 57.674 kDa
- Gene ID
- 1736
- UniProt
- O60832
- Pathways
- Telomere Maintenance
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