DOK5 antibody

Catalog No. ABIN6290290

Product Details anti-DOK5 Antibody

Target: DOK5 (Docking Protein 5 (DOK5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human DOK5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highest expression in skeletal muscle, lower in brain, heart and kidney, Also detected in activated peripheral blood T-lymphocytes

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5 (DOK5 Products)

Synonyms: C20orf180 antibody, 2700055C10Rik antibody, RGD1562846 antibody, docking protein 5 antibody, Docking protein 5 antibody, DOK5 antibody, dok5 antibody, Dok5 antibody

Background: The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 35.464 kDa

Gene ID: 55816

UniProt: Q9P104