ADAM11 antibody
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- Target See all ADAM11 Antibodies
- ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADAM11 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human ADAM11
- Isotype
- IgG
- Top Product
- Discover our top product ADAM11 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Comment
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Expressed predominantly in brain, Slightly detected or not at all in other tissues
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))
- Alternative Name
- ADAM11 (ADAM11 Products)
- Synonyms
- DKFZp459F101 antibody, AW060611 antibody, Mdc antibody, MDC antibody, mdc antibody, mdc11a antibody, xMDC11 antibody, ADAM metallopeptidase domain 11 antibody, a disintegrin and metallopeptidase domain 11 antibody, ADAM metallopeptidase domain 11 L homeolog antibody, ADAM11 antibody, adam11 antibody, Adam11 antibody, adam11.L antibody
- Background
- This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Molecular Weight
- 83.418 kDa
- Gene ID
- 4185
- UniProt
- O75078
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